Method
We offer a validated metabolomics platform that provides comprehensive information on canine metabolism. The blood testing method is optimized for dogs and is based on the well-established metabolomics method NMR (Nuclear Magnetic Resonance) spectroscopy. The measurement procedure provides vast spectral data, which is transformed into quantitative metabolite concentrations, which can be again used to detect systemic metabolic changes.
Metabolites
The targeted, quantitative metabolomics platform quantifies over 100 different metabolite measurands from a single 100 µl serum or plasma sample in one measurement. The platform covers a wide range of different compounds from multiple molecular groups, including amino acids, fatty acids, lipoproteins, cholesterols, triglycerides, glycolysis-related measurands, fluid balance –related measurands, and the inflammatory marker glycoprotein acetyls.
Scientific publications
The science-based blood analysis platform provides a comprehensive, accurate and reliable solution for metabolomics research of dogs, for example, to determine the metabolic effects of diseases, medications, and lifestyles.
PHYSIOLOGY
5/2023 Metabolomics during canine pregnancy and lactation
2/2023 The metabolic differences of anestrus, heat, pregnancy, pseudopregnancy, and lactation in 800 female dogs
2/2022 Age, breed, sex and diet influence serum metabolite profiles of 2000 pet dogs
12/2021 Seasonal variation in serum metabolites of northern European dogs
DISEASES
10/2022 Metabolic fingerprinting of dogs with idiopathic epilepsy receiving a ketogenic medium-chain triglyceride (MCT) oil
7/2022 Serum metabolomic profiles in dogs with chronic enteropathy
7/2022 Metabolic changes associated with two endocrine abnormalities in dogs: elevated fructosamine and low thyroxine
4/2022 Metabolomic Abnormalities in Serum from Untreated and Treated Dogs with Hyper- and Hypoadrenocorticism
3/2022 Metabolomic serum abnormalities in dogs with hepatopathies
6/2021 Serum NMR metabolomics uncovers
multiple metabolic changes in phenobarbital-treated dogs
1/2021 High serum creatinine concentration is
associated with metabolic perturbations in dogs