Our technology

Metabolites

Our validated dog-specific NMR metabolomics platform offers comprehensive information on canine metabolism by quantitating 123 different metabolite measurands from a single 100 µl serum or plasma sample. Our technology covers a wide range of different compounds, including amino acids, fatty acids, lipoproteins, cholesterols and triglycerides, glycolysis- related measurands, albumin and creatinine, and the inflammatory marker glycoprotein acetyls. 

Amino acids (mmol/l)	Fluid balance	Glycolysis related metabolites (mmol/l)	Inflammation (mmol/l)	Cholesterol (mmol/l)	Triglycerides (mmol/l)	Fatty acids (mmol/l and % of total fatty acids)	Lipoprotein particles (mmol/l)
Alanine	Creatinine (mmol/l)	Glucose	Glycoprotein acetyls	Total cholesterol	Total triglycerides	Total fatty acids	HDL particles
Glutamine*	Albumin (g/l)	Lactate		Esterified cholesterol	HDL triglycerides	Saturated fatty acids	LDL particles
Glycine**		Pyruvate**		Free cholesterol	LDL triglycerides	Polyunsaturated fatty acids	VLDL particles
Histidine		Citrate		HDL cholesterol	VLDL triglycerides	Omega-3 fatty acids	Lipids in HDL particles
Branched-chain amino acids		Acetate		LDL cholesterol		Omega-6 fatty acids	Lipids in LDL particles
Isoleucine				VLDL cholesterol		Arachidonic acid	Lipids in VLDL particles
Leucine						Docosahexaenoic acid	Lipoprotein particle size (nm)
Valine						Docosapentaenoic acid	Mean diameter of HDL particles
Total BCAA						Linoleic acid	Mean diameter of LDL particles
Aromatic amino acids						Oleid acid	Mean diameter of VLDL particles
Phenylalanine						Palmitic acid	8 lipoprotein subclasses
Tyrosine						Stearic acid	Small HDL particles
Amino acid ratios						Fatty acid ratios	Large HDL particles
Alanine/BCAA						Ratio of omega-6/ omega-3 fatty acids	Very large HDL particles
Alanine/Valine							Small LDL particles
BCAA/Tyrosine							Large LDL particles
Glycine/BCAA							Small VLDL particles
Glycine/Valine							Large VLDL particles
Phenylalanine/ Tyrosine							Very large VLDL particles
							Lipoprotein subclass composition (mmol/l)
							Particle concentration
							Total lipids
							Total cholesterol
							Esterified cholesterol
							Free cholesterol
							Triglycerides
							Phospholipids

Publications

Due to its robustness and quantitative results, our canine NMR metabolomics platform is a great research tool for various metabolic research questions related to diseases, medications, and physiology. 

Check out scientific publications utilising the dog metabolomics platform

Research services

Are you interested in using our technology for research purposes? Contact us! We will provide you instructions and requirements for samples and shipping. After that we will analyse your samples and deliver you the quantitative results.